We are a computational research lab located at the Department of Genetics, Microbiology and Statistics of the University of Barcelona (UB). Our main interest is the interplay between genetic variation, gene expression and complex traits. We study the effects of genetic variants in molecular (both bulk and single cell transcriptome, epigenome, etc.) and organismic phenotypes at a population level, and their impact on health and disease. We have expertise in the development of novel statistical ...

sqtlseeker2-nf

A pipeline for splicing quantitative trait loci (sQTL) mapping.

The pipeline performs the following analysis steps:

• Index the genotype file
• Preprocess the transcript expression data
• Test for association between ...

mvgwas-nf

A pipeline for multi-trait genome-wide association studies (GWAS) using MANTA.

The pipeline performs the following analysis steps:

• Split genotype file
• Preprocess phenotype and covariate ...