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Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures
Type: Scipion
Creators: Carlos Oscar Sorzano Sanchez, Roberto Melero, Marta Martinez
Submitter: Laura del Cano
Scipion is a workflow engine mostly for Cryo-Electron Microscopy image processing. In this extremely simple workflow, we load the Relion 3.0 tutorial data and process it to 2.9A resolution.
This WF is based on the official Covid19-Galaxy assembly workflow as available from https://covid19.galaxyproject.org/genomics/2-assembly/ . It has been adapted to suit the needs of the analysis of metagenomics sequencing data. Prior to be submitted to INDSC databases, these data need to be cleaned from contaminant reads, including reads of possible human origin.
The assembly of the SARS-CoV-2 genome is performed using both the Unicycler and the SPAdes assemblers, similar to the original WV.
To ...
RNA-RNA interactome analysis using ChiRA tools suite. The aligner used is CLAN.
RNA-RNA interactome analysis using ChiRA tools suite. The aligner used is BWA-MEM.
Abstract CWL Automatically generated from the Galaxy workflow file: CLM-FATES_ ALP1 simulation (5 years)
Genome assembly: Unicycler-based WF for Klebsiella pneumoniae [Wick et al. Microbial genomics 2017]
Genome assembly: Flye-based WF for highly repetitive genomes [Schmid et al. NAR 2018]
Basic workflows inspired by the Nanopolish tutorials