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Kataegis refers to the occurrence of regional hypermutation and is a phenomenon observed in a wide range of malignancies. Using changepoint detection katdetectr aims to identify putative kataegis foci from common data-formats housing genomic variants. Katdetectr has shown to be a robust package for the detection, characterization and visualization of kataegis.

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Space: Independent Teams

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lmjxteam2

Space: Independent Teams

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Our research group Methods and Algorithms for Bioinformatics belongs to French National Center for Scientific Research (CNRS) and is hosted by the Computer Science Dpt of University of Montpellier (in the LIRMM joint unit UMR 5506). We offer interactive web services, software, and programming libraries for bioinformatics on the ATGC bioinformatic platform. Well known software from our group are for instance ...

Medical bioinformatics group of the Medical Proteome Center at the Ruhr University Bochum

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Space: Independent Teams

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Research areas: - Structure, evolution and maintenance of telomeres and their roles in chromosome stability, DNA repair and plant speciation - Epigenetic mechanisms in the regulation of gene expression, chromatin assembly, genome stability and telomere homeostasis - Transcription, replication and DNA repair in the context of nuclear and nucleolar architecture

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