Workflows
What is a Workflow?
Analyse Bulk RNA-Seq data in preparation for downstream Pathways analysis with MINERVA
Type: Galaxy
Creators: Iacopo Cristoferi, Helena Rasche, Clinical Bioinformatics Unit, Pathology Department, Eramus Medical Center
Submitter: Helena Rasche
This portion of the workflow produces sets of feature Counts ready for analysis by limma/etc.
Type: Galaxy
Creators: Iacopo Cristoferi, Helena Rasche, Clinical Bioinformatics Unit, Pathology Department, Eramus Medical Center
Submitter: Helena Rasche
Analyse Bulk RNA-Seq data in preparation for downstream Pathways analysis with MINERVA
To discover causal mutations of inherited diseases it’s common practice to do a trio analysis. In a trio analysis DNA is sequenced of both the patient and parents. Using this method, it’s possible to identify multiple inheritance patterns. Some examples of these patterns are autosomal recessive, autosomal dominant, and de-novo variants, which are represented in the figure below. To elaborate, the most left tree shows an autosomal dominant inhertitance pattern where the offspring inherits a faulty ...
