The ultimate-level complexity workflow is one among a collection of workflows designed to address tasks up to CTF estimation. In addition to the functionalities provided by layer 0 and 1 workflows, this workflow aims to enhance the quality of both **acquisition images** and **processing**. **Quality control protocols** … **Combination of methods** * **CTF consensus** * New methods to compare ctf estimations * CTF xmipp criteria (richer parameters i.e. ice detection) **Advantages**: * Control of the acquisition quality * Robust estimations to continue with the processing