Image processing from movies to micrographs, including CTF estimation and quality filters for image curation. **Adapting to Tilted Samples** To process tilted experiments, use ”tilted” templates. These are modified workflows tailored to handle high drift and lower resolution commonly observed in tilted samples. Key adjustments include: * **Motion Correction Filters**: Max per-frame shift = 30; Global drift = 120. * **CTF Consensus Filters**: Adapted to 6.5 Å and 8.5 Å resolution cutoffs. * **Defocus Sampler**: Trains with 500 images to select 25 diverse examples, ensuring a generalizable picking model.